By Sree Chitra Tirunal Institute for Medical Sciences & Technology(SCTIMST)
Bone fillers are in regular use in orthopedics and dentistry to cover the gaps of implant or graft placement. Calcium salts are preferred rather than ceramic material for bone filling purpose. The advent of calcium phosphate cement was a significant development because it gave a mouldable, resorbable and bioactive material for filling applications. This cement helps in the management of bone defects in bone, spine and maxillofacial structures.
Product Design and Silent Features
Calcium phosphate cements are new-generation bone filler materials, combining mouldability, resorbability and bioactivity. They are designed as powder-liquid combination, which upon mixing, gives a self-setting putty. Upon setting, it will get converted to hydroxyapatite.
Mixing the powder with the liquid in the prescribed ratio will give a self-setting putty. The setting time will be 12-16 minutes and after setting the mass will develop a strength of 10-12 MPa, comparable to spongy bone. This will get resorbed in vivo and get replaced with bone in a period of 6-9 months.
The intellectual property rights of the production process are protected.
The know-how for the calcium phosphate cement has been licensed. Multiple technology transfers are envisaged.
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