By Sree Chitra Tirunal Institute for Medical Sciences & Technology(SCTIMST)
Bone defect repair in orthopedic, spine and maxillofacial surgeries calls for a mouldable bioactive cement material which will be helpful in grafting inaccessible sites and to build contours. This new bioactive calcium sulfate cement is a highly affordable option for bone filling. It sets by mixing with water and integrate with bone during 6-9 months.
Product Design and Silent Features
Calcium sulfate cement comes as an alternative to its phosphate counterpart, retaining the properties like mouldability, resorbability and bioactivity. It designed as powder, which upon mixing with water gives self-setting putty. Pure calcium sulfate is modified with hydrogen orthophosphate ions so as to impart better biocompatibility and slower resorption.This technology has been indigenously developed and translated to clinical application. The intellectual property rights of the production process are protected.
This is simple and affordable bone filler cement based on calcium sulfate, setting in water medium. The setting time will be 12-16 minutes and after setting the mass will develop strength of 10-12 MPa, comparable to spongy bone.
Pre-clinical studies completed. Clinical trials in progress.
Technology is transferred to an industry. Multiple transfers are envisaged.
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