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De-cellularised Bovine Pericardium for Cardiovascular Patch Applications
By Sree Chitra Tirunal Institute for Medical Sciences & Technology(SCTIMST)
In India it is estimated that 180,000 children are born with Coronary Heart Disease (CHD) every year. Of these nearly 60,000 to 90,000 suffer from critical CHD requiring early intervention. Decellularised animal tissue provide excellent choice for fabrication of cardiac patches and valved conduits because of their performance characteristics compared to materials such as metals, plastics or fabrics.
Product Design and Silent Features
The animal tissue was collected from well monitored, healthy, disease free herds as per International standards, ISO 22442-2 and is tested for BSE and other relevant bovine diseases.This traceable tissue of biomedical quality was subjected to a de-cellularisation process developed. The process renders it less immunogenic and less calcifying at the same allows better host tissue incorporation. De-cellularised bovine pericardium thus developed was subjected to preclinical testing as per relevant international standards to qualify its use as cardiovascular patch.
Development Stage
Industry can associate to take forward the clinical trial and further commercialization.
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