Fibrin Wafer for Curcumin Delivery
By Sree Chitra Tirunal Institute for Medical Sciences & Technology(SCTIMST)
Most of the anti-cancer drugs are toxic to different cell types. Therefore, local delivery of cancer drug at the surgical site has effective implications in cancer treatment to prevent remission. Curcumin conjugated to human albumin (Curc-Alb) has potent apoptotic effect on cancer cell which can be used to prevent and treat cancer.
Product Design and Silent Features
Fibrin wafer incorporated with Curc-Alb has been designed to be implanted at the surgical site.Salient features are fibrin is adhesive to surgical, bleeding tissue; so, application is easy. Added advantage is it can be hemostatic and helps in arresting excessive bleeding. A single product for inducing haemostasis and for sustained release of a proven drug in soluble form, constructed using only human proteins in a stable, ready-to-use form: Patents : Alb-Curc (PCT/IN2014/000338) Fibrin wafer / disc (PCT/IN2014/000338)
Development Stage
Industry shall associate with the development in conduct of clinical trials and further commercialization.
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